Dehydration at Night + Kidney Health
Links
What works
from http://www.glycoboy.com/ankylosingSpondylitis.asp
Possible Cause: Hypercalcemia
- KickAS forum: Dehydration at Night & Kidney Health
http://www.kickas.org/ubbthreads/showflat.php?Cat=0&Number=198969
What works
- Taking a Multivitamin
This works quite well. I don't know what nutrient is helping out, so I will just list out the brand and the ingredients of my multi vitamin. I will experiment with other multi vitamins and see if they also help.Eventually I will figure it out.
The supplement is from 'Ion Health' in NSW Australia, it contains : -
- betacarotene, b vitamins, vit c, vit d, vit e, vit h, folic acid, inositol, choline bitartate, bioflavanoids, bromelains, cysteine, lysine, taurine, glutamine, phosphate, magnesium, potassium, zinc, chromium, selenium, manganese, iodine, copper gluconate
- 2005.04.21 : I tries several of the above separately and it looks like it is the bromelain that is helping? Unfortunately most bromelain tablets have starch added so you will need to test with iodine. The iodine will change to a bluish black colour if there is starch.
- Sleeping on my belly
This works a bit better than the multivitamin. But this is so very very uncomfortable that I don't sleep very well.
- Fasting
I had a bad tummy bug once and couldn't keep food down. My gut was cleared out pretty quick (the runs) and after which I was in no pain. Not only was I in no pain but I felt really good, my mind was clear, I slept really well and had no dehydration during the night.
from http://www.glycoboy.com/ankylosingSpondylitis.asp
"One more. An NSAID medication I took a few years back killed a particular portion of each kidney (Papillary Necrosis). I became unusually susceptible to dehydration, and had to drink large amounts of water to get my urine colorless. Now, I can keep it colorless by drinking normal amounts of water."
Possible Cause: Hypercalcemia
- Looks like hypercalcemia results from excessive leukocytes / macrophage activity. The increases macrophage activity causes an increase in Calcitriol, and the high levels of Calcitriol can cause "increased urination (especially at night)" (see: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682335.html)
Quote from: http://www.pulmonologychannel.com/sarcoidosis/
- "There are many different granulomatous diseases, from Crohn's disease to tuberculosis."
"The cells that make up a granuloma are from the immune system. The immune system is the body's defense against disease and illness. Its major players are the macrophages and leukocytes, cells that originate in the bone marrow and travel through the lymphatic vessels to different areas of the body."
- "Granulomatous disorders: High levels of calcitriol may be found in patients with sarcoidosis and other granulomatous diseases. In these disorders, the increased level of calcitriol results from production within the macrophages, which constitute a large portion of some granulomas."
- "'Granuloma' are a special type of inflammation. They are an aggregation of lymphocytes, monocytes, macrophages and epithelioid giant cells. They form in soft tissues throughout the body. Although they are often found in the liver, kidney and brain, most commonly they are found in the interstitial tissue of the lungs."
- "There are many different granulomatous diseases, from Crohn's disease to tuberculosis."
- Quotes from: http://www.emedicine.com/emerg/topic260.htm
- "Hypercalcemia associated with renal calculi, joint complaints, and ulcer disease is more likely to be caused by hyperparathyroidism."
- "Hypercalcemia can produce a number of nonspecific findings, as follows:
* Hypertension and bradycardia may be noted in patients with hypercalcemia, but this is nonspecific.
* Abdominal examination may suggest pancreatitis or the possibility of an ulcer.
* Patients with long-standing elevation of serum calcium may have proximal muscle weakness that is more prominent in the lower extremities; they also may have bony tenderness to palpation.
* Hyperreflexia and tongue fasciculations may be present.
* Anorexia or nausea may occur.
* Polyuria and dehydration are common.
* Lethargy, stupor, or even coma may be observed." - "Granulomatous disorders: High levels of calcitriol may be found in patients with sarcoidosis and other granulomatous diseases. In these disorders, the increased level of calcitriol results from production within the macrophages, which constitute a large portion of some granulomas."
-
- "Signs and symptoms of hypercalcemia to report to the health care provider:
-
- Lethargy.
- Fatigue.
- Confusion.
- Loss of appetite.
- Nausea/vomiting.
- Constipation.
- Excessive thirst."
- Calcitriol can cause "increased urination (especially at night)" and a host of other interesting side effects which are common enough in AS. This leads one to think that perhaps people with AS have elevated Caclitriol levels? I am not sure, what I do know is that we tend to have high levels of serum calcium (ie: high blood concentraion of caclcium).
Quotes from: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682335.html -
- "Calcitriol is a form of vitamin D that keeps the amount of calcium in the blood from becoming too low (hypocalcemia)."
- "increased urination (especially at night)" (as an adverseside effect of taking Calcitriol)
- [here is a list of side effects from Calcitriol:]
* weakness
* headache
* sluggishness
* upset stomach
* vomiting
* dry mouth
* constipation
* muscle pain
* bone pain
* metal taste
* increased thirst
* decreased appetite
* weight loss
* increased urination (especially at night)
* changes in vision
* changes in mental awareness
